Week 1 · Sun, Oct 18 · 8:05 PM ET

Arizona Cardinals vs Los Angeles Rams: prediction & pick

When Arizona Cardinals and Los Angeles Rams meet, our simulation gives the edge to Los Angeles Rams. Our projection has LAR favored by roughly 4.5 points, a win probability near 64%, and a projected final of ARI 21 – LAR 25.

Against the spread

Comparing our projected margin to the posted line of -13.5 for the home team surfaces a gap the model wants to bet. The recommendation is ARI +13.5, an edge of about 9.0 points in our favor.

Total (over/under)

Totals-wise, the simulation expects roughly 45.5 points while the book has hung 47.5. That points to the Under 47.5, with about 2.0 points of under edge.

The projection

Running the matchup through the model produces a projected final score of ARI 21 – LAR 25, built from each team's power rating, home-field advantage, and pace. See how the model works for the full methodology.

Betting involves risk. Lines move — always confirm the current number at your sportsbook before betting. 21+ where legal.

Bottom line: the model rates this a Strong play at 88% confidence. As always, shop for the best available number and size the bet to your bankroll — a single game never makes or breaks a season.