Week 1 · Sun, Sep 13 · 5:00 PM ET

Buffalo Bills vs Houston Texans: prediction & pick

The model has run the numbers on Buffalo Bills at Houston Texans and it likes Buffalo Bills. Our projection has BUF favored by roughly 0.5 points, a win probability near 52%, and a projected final of BUF 23 – HOU 23.

Against the spread

Where the book sits at 1.5 on HOU, our simulation disagrees by enough to make this a live spread play. The recommendation is HOU +1.5, an edge of about 1.0 points in our favor.

Total (over/under)

On the total, the model projects around 45.5 combined points versus a market number of 44.5. That points to the Over 44.5, with about 1.0 points of over edge.

The projection

Running the matchup through the model produces a projected final score of BUF 23 – HOU 23, built from each team's power rating, home-field advantage, and pace. See how the model works for the full methodology.

Betting involves risk. Lines move — always confirm the current number at your sportsbook before betting. 21+ where legal.

Bottom line: the model rates this a Lean at 56% confidence. As always, shop for the best available number and size the bet to your bankroll — a single game never makes or breaks a season.