NFLComputerPicksDenver Broncos vs San Francisco 49ers: prediction & pick
The model has run the numbers on Denver Broncos at San Francisco 49ers and it likes San Francisco 49ers. Our projection has SF favored by roughly 6.0 points, a win probability near 69%, and a projected final of DEN 19 – SF 25.
Against the spread
Where the book sits at -2.5 on SF, our simulation disagrees by enough to make this a live spread play. The recommendation is SF -2.5, an edge of about 3.5 points in our favor.
Total (over/under)
On the total, the model projects around 44.0 combined points versus a market number of 46.5. That points to the Under 46.5, with about 2.5 points of under edge.
The projection
Running the matchup through the model produces a projected final score of DEN 19 – SF 25, built from each team's power rating, home-field advantage, and pace. See how the model works for the full methodology.
Bottom line: the model rates this a Strong play at 71% confidence. As always, shop for the best available number and size the bet to your bankroll — a single game never makes or breaks a season.