Week 1 · Sun, Sep 20 · 8:25 PM ET

Seattle Seahawks vs Arizona Cardinals: prediction & pick

Arizona Cardinals host Seattle Seahawks in a matchup where the model sides with Arizona Cardinals. Our projection has ARI favored by roughly 1.0 points, a win probability near 53%, and a projected final of SEA 22 – ARI 23.

Against the spread

Comparing our projected margin to the posted line of 10 for the home team surfaces a gap the model wants to bet. The recommendation is ARI +10, an edge of about 11.0 points in our favor.

Total (over/under)

Totals-wise, the simulation expects roughly 45.0 points while the book has hung 44.5. That's too tight to bet with confidence — the total is best left alone here.

The projection

Running the matchup through the model produces a projected final score of SEA 22 – ARI 23, built from each team's power rating, home-field advantage, and pace. See how the model works for the full methodology.

Betting involves risk. Lines move — always confirm the current number at your sportsbook before betting. 21+ where legal.

Bottom line: the model rates this a Strong play at 88% confidence. As always, shop for the best available number and size the bet to your bankroll — a single game never makes or breaks a season.